Todd tried screaming towards her - without any effect, so he just started to run towards the toilet, thinking how was he going to scale the enormous object. Somewhere on the way he noticed his sister was looking down at her toes, probably marvelling them again, she used to spend hours admiring herself everywhere, not necessarily in front of the mirror. While normally that was merely annoying, for instance when she got to the bathroom first and forced Todd to wait forever for her to leave - but now he was thankful it gave him a lot of time to act. This gave him an idea - maybe if he got close enough to one of her toes, then she would notice him... it seemed risky but could work.
After changing his route, Todd watched the warehouse sized feet with amazement - well, they were pretty nice, shapely with smooth skin - and that was even from this close. But he did not have time to gawk, as when he was mere inches from them, Annie started wiping - threatening his communication efforts. He immediately started screaming, jumping and waving - again having no effect, but thankfully she did wiggle her toes and looked at them for the last time, before rising up. This time, she could see him on the flat blank background of the bathroom tiles - but must have not been aware that he was a human, as she pulled her feet away and looked at him with disgust. "Oh god, does she think I'm a bug of some kind..." Todd thought and redoubled his efforts. Annie leaned forward with a piece of paper held in a stretched arm, presumably to crush him - but when her face was closer, she must have noticed his humanly features and backed away. "Oh my god", she spoke with volume of a thunderstorm, "is this... are you a human?" He covered his ears and nodded - but was doubtful she could make out his movements.
But regardless, she leaned forward and placed a monstrous hand in front of him palm up and asked - or ordered - him to get on. Confronting a three story high side of the hand, he figured it may be better to try to climb one of the fingers or - better yet - fingernails, so he begun to come round it. Annie must have noticed by now how small he was in comparison and that ascending her hand directly would be impossible, but she just watched him. Eventually, as he boarded one of her nails - what seemed to be the only viable place for him to get on - she moved the hand carefully towards her face.
Looking at her impossibly large form from the floor level was one thing - but watching pool sized eyes study him wide open was something completely new... It seemed to Todd that she was some sort of Goddess penetrating him with her gaze in silence. The only thing she could say was: "Todd?", which was again significantly too loud for Todd - but this time noticed him covering his ears and added whispering "sorry..."
Annie then...